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N-Methylspiperone

Structure via PubChem · Public domain (PubChem)

EntityQ10859672· pop 5· linked from 505 articles

N-Methylspiperone

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'''N-Methylspiperone (NMSP''') is a derivate of spiperone that is used to study the dopamine and serotonin neurotransmitter systems. Labeled with the radioisotope carbon-11, it can be used for positron emission tomography.

Chemical data

Formula
C24H28FN3O2
Molecular weight
409.5 g/mol
IUPAC name
8-[4-(4-fluorophenyl)-4-oxobutyl]-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
SMILES
CN1CN(C2(C1=O)CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4
InChIKey
QHJLPOSPWKZACG-UHFFFAOYSA-N
XLogP
3.2
Polar surface area
43.9 Ų
H-bond donors
0
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
409.216555
Show 3 more facts
chemical formula
C₂₄H₂₈FN₃O₂
canonical SMILES
CN1CN(C2(C1=O)CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4
subject has role
dopamine agonist
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

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Contents
  • References

'''N-Methylspiperone (NMSP''') is a derivate of spiperone that is used to study the dopamine and serotonin neurotransmitter systems. Labeled with the radioisotope carbon-11, it can be used for positron emission tomography.

== References ==

Excerpted from Wikipedia’s “N-Methylspiperone” article, available under the CC BY-SA 4.0 licence.

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