naftifine
Also known as Naftin, Naftifin, Naftifina, Naftifinum, trans-N-cinnamyl-N-methyl-(1-naphthylmethyl)amine, (E)-N-cinnamyl-N-methyl-1-naphthalenemethylamine
Naftifine hydrochloride (brand names include Exoderil and Naftin) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis (topical fungal infections).
Chemical data
- Formula
- C21H21N
- Molecular weight
- 287.4 g/mol
- IUPAC name
- (E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine
- SMILES
- CN(C/C=C/C1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32
- InChIKey
- OZGNYLLQHRPOBR-DHZHZOJOSA-N
- XLogP
- 5.1
- Polar surface area
- 3.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Research
237 papers~1 min read
Article
1 sectionsContents
- References
Naftifine hydrochloride (brand names include Exoderil and Naftin) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis (topical fungal infections).
Naftifine was invented at the Sandoz Research Institute in Vienna, Austria. It was the first successful antifungal medication of the allylamine class.