etofenamate

Also known as BAY-D-1107, WHR-5020, SID11112716, TVX-485, SID144204169

Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain. It is available for topical application as a cream, a gel or as a spray.

Chemical data

Formula: C18H18F3NO4
Molecular weight: 369.3 g/mol
IUPAC name: 2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate
SMILES: C1=CC=C(C(=C1)C(=O)OCCOCCO)NC2=CC=CC(=C2)C(F)(F)F
InChIKey: XILVEPYQJIOVNB-UHFFFAOYSA-N
XLogP: 4.7
Polar surface area: 67.8 Å²
H-bond donors: 2
H-bond acceptors: 8
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule
Indications: Myalgia, Arthralgia

via ChEMBL · EBI

Research

120 papers

Clinical Efficacy and Safety Profile of Topical Etofenamate in the Treatment of Patients with Musculoskeletal Disorders: A Systematic Review.Pain and therapy · 2020
Efficacy and Safety of an Etofenamate Medicated Plaster for Acute Ankle Sprain: A Randomized Controlled Trial.Orthopaedic journal of sports medicine · 2021
Allergic contact dermatitis from etofenamate without cross-sensitization to other anthranilic acid derivatives.Dermatology (Basel, Switzerland) · 2003
[Allergic contact eczema to etofenamate and dwarf pine oil].Sportverletzung Sportschaden : Organ der Gesellschaft fur Orthopadisch-Traumatologische Sportmedizin · 1990
Effectiveness of etofenamate for treatment of knee osteoarthritis: a randomized controlled trial.Therapeutics and clinical risk management · 2016

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 369.118793
Has use: medication

Show 4 more facts

chemical formula: C₁₈H₁₈F₃NO₄
canonical SMILES: C1=CC=C(C(=C1)C(=O)OCCOCCO)NC2=CC=CC(=C2)C(F)(F)F
subject has role: non-steroidal anti-inflammatory drug
Commons category: Etofenamate

Sources (2)

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Encyclopedic overview

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Contents

References

Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain. It is available for topical application as a cream, a gel or as a spray.

Etofenamate is very toxic to aquatic life, with long lasting effects.

Excerpted from Wikipedia’s “etofenamate” article, available under the CC BY-SA 4.0 licence.

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