NAP1L4
Sign in to saveAlso known as NAP1L4b, NAP2, NAP2L, hNAP2, nucleosome assembly protein 1 like 4
Nucleosome assembly protein 1-like 4 is a protein that in humans is encoded by the NAP1L4 gene.
In the Vinony graph
Within Vinony's link graph, NAP1L4 is referenced by 2 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.
It is catalogued under topics including Genes on human chromosome 11 and Human proteins.
Its subject is documented across 7 Wikipedia language editions.
Gene data
NAP1L4- Name
- nucleosome assembly protein 1 like 4
- Type
- protein-coding
- Position
- 2,944,429–2,992,416 (−)
- Aliases
- NAP1L4b, NAP2, NAP2L, hNAP2
- Ensembl
- ENSG00000273562
- RefSeq RNA
- NM_001369375.1, NM_001369376.1, NM_001369377.1, NM_001369378.1, NM_001369379.1
- RefSeq protein
- NP_001356304.1, NP_001356305.1, NP_001356306.1, NP_001356307.1, NP_001356308.1
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Cellular component
via MyGene.info
Gene · Ensembl
nucleosome assembly protein 1 like 4
- Symbol
- NAP1L4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:2,944,429-2,992,416
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 133933
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4676
- chromosome
- human chromosome 11
- genomic start
- 2965667
- genomic end
- 3013607
- cytogenetic location
- 11p15.4
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Nucleosome assembly protein 1-like 4 is a protein that in humans is encoded by the NAP1L4 gene.
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer.
Excerpted from Wikipedia’s “NAP1L4” article, available under the CC BY-SA 4.0 licence.