nicodicodine
Sign in to saveNicodicodine is an opioid developed as a cough suppressant and analgesic. Synthesized in 1904, it is not commonly used, but has activity similar to other opioids. Nicodicodine is metabolised in the liver by demethylation to produce 6-nicotinoyldihydromorphine, and subsequently further metabolised to dihydromorphine. Since the final active metabolite is the slightly stronger opiate dihydromorphine rather than morphine, nicodicodine can be expected to be marginally more potent and longer acting than nicocodeine. Side effects are similar to those of other opioids and include itching, nausea and r
Key facts
- Drug.Watchedfields
- changed
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 447732381
- Drug.IUPAC_name
- (5alpha,6alpha)-3-Methoxy-17-methyl-4,5-epoxymorphinan-6-yl pyridine-3-carboxylate
- Drug.image
- Nicodicodeine.svg
- Drug.image_class
- skin-invert-image
- Drug.alt
- Structural formula
- Drug.width
- 210
- Drug.image2
- Nicodicodeine molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.alt2
- Ball-and-stick model
- Drug.width2
- 220
- Drug.legal_AU
- S2
- Drug.legal_BR
- A2
- Drug.legal_DE
- Anlage II
- Drug.legal_UK
- Class B
- Drug.legal_UN
- narcotic schedules i and iii
- Drug.routes_of_administration
- Oral, intravenous
via Wikipedia infobox
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 406.189
Show 4 more facts
- chemical formula
- C₂₄H₂₆N₂O₄
- canonical SMILES
- CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(CC4)OC(=O)C6=CN=CC=C6
- isomeric SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](CC4)OC(=O)C6=CN=CC=C6
- Commons category
- Nicodicodeine
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
1 sectionsContents
- References
Nicodicodine is an opioid developed as a cough suppressant and analgesic. Synthesized in 1904, it is not commonly used, but has activity similar to other opioids. Nicodicodine is metabolised in the liver by demethylation to produce 6-nicotinoyldihydromorphine, and subsequently further metabolised to dihydromorphine. Since the final active metabolite is the slightly stronger opiate dihydromorphine rather than morphine, nicodicodine can be expected to be marginally more potent and longer acting than nicocodeine. Side effects are similar to those of other opioids and include itching, nausea and respiratory depression.
==References==
Excerpted from Wikipedia’s “nicodicodine” article, available under the CC BY-SA 4.0 licence.
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