pholcodine

Also known as 3-morpholinoethylmorphine, morpholinylethylmorphine, 3-(2-morpholinoethyl)morphine, beta-morpholinoethylmorphine, tetrahydro-1,4-oxazinylmethylcodeine, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)morphinan-6-alpha-ol, 3-(2-(4-morpholinyl)ethyl)morphine

Pholcodine is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine.

Key facts

Drug.image: Pholcodine.svg
Drug.image_class: skin-invert-image
Drug.width: 200
Drug.image2: Pholcodine3DanJ.gif
Drug.width2: 250
Drug.tradename: Logicin, others
Drug.addiction_liability: High
Drug.routes_of_administration: By mouth
Drug.ATC_prefix: R05
Drug.ATC_suffix: DA08
Drug.legal_BR: A2
Drug.legal_CA: Schedule I
Drug.legal_DE

Article

5 sections

Contents

Mechanism of action
Metabolism and excretion
Side effects
Anaphylaxis during general anaesthesia
References

Pholcodine is found in certain cough lozenges, and more commonly as an oral solution, typically 5 mg / 5 ml. Adult dosage is 5-10 ml up to 3-4 times daily. Pholcodine now largely replaces the previously more common codeine linctus, as it has a much lower potential for dependence.