Structure via PubChem · Public domain (PubChem)
benproperine
Sign in to saveBenproperine (INN) is a cough suppressant. It has been marketed in multiple countries in Central America and Europe, as the phosphate or pamoate salts in either tablet, dragée, or syrup form. Trade names include Blascorid in Italy and Sweden, Pectipront and Tussafug in Germany, and Pirexyl in Scandinavia. The recommended dosage for adults is 25 to 50 mg two to four times daily, and for children 25 mg once or twice daily. Adverse effects include dry mouth, dizziness, fatigue, and heartburn.
Chemical data
- Formula
- C21H27NO
- Molecular weight
- 309.4 g/mol
- IUPAC name
- 1-[1-(2-benzylphenoxy)propan-2-yl]piperidine
- SMILES
- CC(COC1=CC=CC=C1CC2=CC=CC=C2)N3CCCCC3
- InChIKey
- JTUQXGZRVLWBCR-UHFFFAOYSA-N
- XLogP
- 5.1
- Polar surface area
- 12.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Cough
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 309.209
Show 4 more facts
- chemical formula
- C₂₁H₂₇NO
- canonical SMILES
- CC(COC1=CC=CC=C1CC2=CC=CC=C2)N3CCCCC3
- defined daily dose
- 75
- Commons category
- Benproperine
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Benproperine (INN) is a cough suppressant. It has been marketed in multiple countries in Central America and Europe, as the phosphate or pamoate salts in either tablet, dragée, or syrup form. Trade names include Blascorid in Italy and Sweden, Pectipront and Tussafug in Germany, and Pirexyl in Scandinavia. The recommended dosage for adults is 25 to 50 mg two to four times daily, and for children 25 mg once or twice daily. Adverse effects include dry mouth, dizziness, fatigue, and heartburn.
==Synthesis==
Excerpted from Wikipedia’s “benproperine” article, available under the CC BY-SA 4.0 licence.