tyloxapol
Sign in to saveAlso known as Superinone
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent (containing mucus and pus) bronchopulmonary secretions, administered by inhalation through a nebulizer or with a stream of oxygen.
Research
757 papers- The effect of Tyloxapol on the metabolome of Mycobacterium tuberculosis.Journal of microbiological methods · 2024
- Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation.Journal of orthopaedic translation · 2021
- Lipopolysaccharide and tyloxapol accelerate the development of atherosclerosis in mice.Lipids · 2022
- Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2023
- Tyloxapol inhibits ESX-1 secretion in Mycobacterium marinum.Journal of bacteriology · 2026
via PubMed
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent (containing mucus and pus) bronchopulmonary secretions, administered by inhalation through a nebulizer or with a stream of oxygen.
With intraperitoneal injection, tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. This mechanism is used to induce experimental hyperlipidemia in animals.
Excerpted from Wikipedia’s “tyloxapol” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0