tyloxapol
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Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent (containing mucus and pus) bronchopulmonary secretions, administered by inhalation through a nebulizer or with a stream of oxygen.
Research
757 papers- The effect of Tyloxapol on the metabolome of Mycobacterium tuberculosis.Journal of microbiological methods · 2024
- Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation.Journal of orthopaedic translation · 2021
- Lipopolysaccharide and tyloxapol accelerate the development of atherosclerosis in mice.Lipids · 2022
- Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2023
- Tyloxapol inhibits ESX-1 secretion in Mycobacterium marinum.Journal of bacteriology · 2026
via PubMed
Wikidata facts
Show 4 more facts
- chemical formula
- C₁₇H₂₈O₃
- defined daily dose
- 5
- subject has role
- surfactant
- canonical SMILES
- Cc1cc(C(C)(C)CC(C)(C)C)cc(Cc2cc(C(C)(C)CC(C)(C)C)cc(Cc3cc(C(C)(C)CC(C)(C)C)ccc3OCCO)c2OCCO)c1OCCO
Sources (4)
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Encyclopedic overview
1 sectionsContents
- References
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent (containing mucus and pus) bronchopulmonary secretions, administered by inhalation through a nebulizer or with a stream of oxygen.
With intraperitoneal injection, tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. This mechanism is used to induce experimental hyperlipidemia in animals.
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