oleandrin
Sign in to saveAlso known as Neriostene, Neriolin, Folinerin, Foliandrin, Anvirzel, Oleandrina
Oleandrin is a cardiac glycoside found in the poisonous plant oleander (Nerium oleander L.). As a main phytochemical of oleander, oleandrin is associated with the toxicity of oleander sap, and has similar properties to digoxin. Oleandrin and other oleander chemicals are potentially toxic to the heart, liver, and kidneys.
Wikidata facts
- Mass
- 576.329833
Show 4 more facts
- chemical formula
- C₃₂H₄₈O₉
- Commons category
- Oleandrin
- isomeric SMILES
- C[C@H]1[C@@H]([C@H](C[C@@H](O1)O[C@H]2CC[C@]3([C@@H](C2)CC[C@@H]4[C@@H]3CC[C@]5([C@@]4(C[C@@H]([C@@H]5C6=CC(=O)OC6)OC(=O)C)O)C)C)OC)O
- canonical SMILES
- CC1C(C(CC(O1)OC2CCC3(C(C2)CCC4C3CCC5(C4(CC(C5C6=CC(=O)OC6)OC(=O)C)O)C)C)OC)O
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Article
13 sectionsContents
- Structure and reactivity
- Synthesis
- Related substances
- Metabolism
- Mechanism of action
- Toxicity
- Symptoms
- Diagnosis
- Treatment
- Traditional medicine
- Political controversy
- Effects on animals
- References
{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 462264921 | ImageFile = Oleandrin.svg | ImageClass = skin-invert-image | ImageSize = 200px | ImageFile2 = Oleandrin 3D BS.png | ImageClass2 = bg-transparent | ImageSize2 = 200px | IUPACName = 16β-(Acetyloxy)-3β-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyloxy)-14-hydroxy-5β-card-20(22)-enolide | SystematicName=(1R,2S,3aS,3bR,5aR,7S,9aS,9bS,11aR)-3a-Hydroxy-7-{[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-9a,11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-2-yl acetate | OtherNames= |Section1= |Section2= | Section3 = }}
Oleandrin is a cardiac glycoside found in the poisonous plant oleander (Nerium oleander L.). As a main phytochemical of oleander, oleandrin is associated with the toxicity of oleander sap, and has similar properties to digoxin. Oleandrin and other oleander chemicals are potentially toxic to the heart, liver, and kidneys.