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EntityQ411532· pop 10· linked from 172 articles

Also known as Neriostene, Neriolin, Folinerin, Foliandrin, Anvirzel, Oleandrina

Oleandrin is a cardiac glycoside found in the poisonous plant oleander (Nerium oleander L.). As a main phytochemical of oleander, oleandrin is associated with the toxicity of oleander sap, and has similar properties to digoxin. Oleandrin and other oleander chemicals are potentially toxic to the heart, liver, and kidneys.

Wikidata facts

Has part
hydrogen
Material used
Nerium oleander
Mass
576.329833
Show 5 more facts
chemical formula
C₃₂H₄₈O₉
Commons category
Oleandrin
isomeric SMILES
C[C@H]1[C@@H]([C@H](C[C@@H](O1)O[C@H]2CC[C@]3([C@@H](C2)CC[C@@H]4[C@@H]3CC[C@]5([C@@]4(C[C@@H]([C@@H]5C6=CC(=O)OC6)OC(=O)C)O)C)C)OC)O
canonical SMILES
CC1C(C(CC(O1)OC2CCC3(C(C2)CCC4C3CCC5(C4(CC(C5C6=CC(=O)OC6)OC(=O)C)O)C)C)OC)O
found in taxon
Nerium oleander
Sources (3)

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Encyclopedic overview

13 sections
Contents
  • Structure and reactivity
  • Synthesis
  • Related substances
  • Metabolism
  • Mechanism of action
  • Toxicity
  • Symptoms
  • Diagnosis
  • Treatment
  • Traditional medicine
  • Political controversy
  • Effects on animals
  • References

{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 462264921 | ImageFile = Oleandrin.svg | ImageClass = skin-invert-image | ImageSize = 200px | ImageFile2 = Oleandrin 3D BS.png | ImageClass2 = bg-transparent | ImageSize2 = 200px | IUPACName = 16β-(Acetyloxy)-3β-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyloxy)-14-hydroxy-5β-card-20(22)-enolide | SystematicName=(1R,2S,3aS,3bR,5aR,7S,9aS,9bS,11aR)-3a-Hydroxy-7-{[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-9a,11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-2-yl acetate | OtherNames= |Section1= |Section2= | Section3 = }}

Oleandrin is a cardiac glycoside found in the poisonous plant oleander (Nerium oleander L.). As a main phytochemical of oleander, oleandrin is associated with the toxicity of oleander sap, and has similar properties to digoxin. Oleandrin and other oleander chemicals are potentially toxic to the heart, liver, and kidneys.

Excerpted from Wikipedia’s “oleandrin” article, available under the CC BY-SA 4.0 licence.

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