P2RY1

Also known as P2Y1, purinergic receptor P2Y1, SARCC

P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.

Gene data

P2RY1

Name: purinergic receptor P2Y1
Type: protein-coding
Position: 152,835,131–152,841,439 (+)
Aliases: P2Y1, SARCC
Ensembl: ENSG00000169860
RefSeq RNA: NM_002563.5
RefSeq protein: NP_002554.1

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

G protein-coupled adenosine receptor signaling pathway cell surface receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway

Molecular function

G protein-coupled ADP receptor activity G protein-coupled ADP receptor activity G protein-coupled ADP receptor activity G protein-coupled receptor activity protein binding ATP binding ATP binding ATP binding

Cellular component

plasma membrane plasma membrane plasma membrane plasma membrane plasma membrane cilium cell surface postsynaptic density

Pathways

Rap1 signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Platelet activation - Homo sapiens (human)Taste transduction - Homo sapiens (human)Hemostasis Hemostasis Signal Transduction Signaling by GPCR Class A/1 (Rhodopsin-like receptors)GPCR downstream signalling

via MyGene.info

Gene · Ensembl

purinergic receptor P2Y1

Symbol: P2RY1
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:152,835,131-152,841,439
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

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Encyclopedic overview

5 sections

Contents

Function
See also
References
Further reading
External links

P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.

== Function ==

Excerpted from Wikipedia’s “P2RY1” article, available under the CC BY-SA 4.0 licence.

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P2RY1

Gene data

Gene Ontology

Pathways

Gene · Ensembl

Encyclopedic overview

Available in 5 languages

What links here490 pages

What links here490 pages