physalaemin
Sign in to saveAlso known as H-Pyr-Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2, XADPNKFYGLM
Physalaemin is a tachykinin peptide obtained from the Physalaemus frog, closely related to substance P. Its structure was first elucidated in 1964.
Research
479 papers- Conformation of physalaemin.European journal of biochemistry · 1984
- Synthesis of physalaemin.Experientia · 1964
- Contractile responses induced by physalaemin, an analogue of substance P, in the rat esophagus.European journal of pharmacology · 2010
- The ontogeny of the antidipsogenic effect of eledoisin and physalaemin in the rat.Appetite · 1987
- The tachykinins neurokinin A and physalaemin stimulate murine thymocyte proliferation.International archives of allergy and applied immunology · 1989
via PubMed
Wikidata facts
- Mass
- 1264.5910436079998
Show 3 more facts
- chemical formula
- C₅₈H₈₄N₁₄O₁₆S
- canonical SMILES
- CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C4CCC(=O)N4
- isomeric SMILES
- C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@@H]4CCC(=O)N4
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Article
3 sectionsContents
- Structure
- Use In Research
- References
Physalaemin is a tachykinin peptide obtained from the Physalaemus frog, closely related to substance P. Its structure was first elucidated in 1964.
Like all tachykinins, physalaemin is a sialagogue (increases salivation) and a potent vasodilator with hypotensive effects.
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