PKP3
Sign in to saveAlso known as plakophilin 3
Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene.
Gene data
PKP3- Name
- plakophilin 3
- Type
- protein-coding
- Position
- 392,574–404,908 (+)
- Ensembl
- ENSG00000184363
- RefSeq RNA
- NM_001303029.2, NM_007183.4
- RefSeq protein
- NP_001289958.1, NP_009114.1
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
plakophilin 3
- Symbol
- PKP3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:392,574-404,908
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 5200
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/11187
- genomic end
- 404908
- genomic start
- 392614
- chromosome
- human chromosome 11
- cytogenetic location
- 11p15.5
- expressed in
- gums
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene.
== Function ==
Excerpted from Wikipedia’s “PKP3” article, available under the CC BY-SA 4.0 licence.