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GeneQ18031046· pop 5· linked from 4 articles

Also known as HRASLS4, HRSL4, PLA1/2-3, RIG1, TIG3, retinoic acid receptor responder 3, PLAAT-4, RARRES3

Retinoic acid receptor responder protein 3 is a protein that in humans is encoded by the RARRES3 gene.

Gene data

PLAAT4
Name
phospholipase A and acyltransferase 4
Type
protein-coding
Aliases
HRASLS4, HRSL4, PLA1/2-3, PLAAT-4, RARRES3, RIG1, TIG3

Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

phospholipase A and acyltransferase 4

Symbol
PLAAT4
Biotype
Protein coding
Organism
Homo sapiens
Location
11:63,529,451-63,549,076
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
48290
genomic end
63313934
genomic start
63536808
cytogenetic location
11q12.3
Sources (3)

via Wikidata · CC0

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Article

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Retinoic acid receptor responder protein 3 is a protein that in humans is encoded by the RARRES3 gene.

Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.

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