PLEKHG4
Sign in to saveAlso known as ARHGEF44, PRTPHN1, SCA4, pleckstrin homology and RhoGEF domain containing G4
Puratrophin-1 is a protein that in humans is encoded by the PLEKHG4 gene.
In the Vinony graph
Within Vinony's link graph, PLEKHG4 is referenced by 5 other articles, and connects out to PubMed, human chromosome 16 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 16.
Its subject is documented across 5 Wikipedia language editions.
Gene data
PLEKHG4- Name
- pleckstrin homology and RhoGEF domain containing G4
- Type
- protein-coding
- Position
- 67,277,510–67,289,499 (+)
- Aliases
- ARHGEF44, PRTPHN1, SCA4
- Ensembl
- ENSG00000196155
- RefSeq RNA
- NM_001129727.3, NM_001129728.2, NM_001129729.3, NM_001129731.3, NM_015432.3
- RefSeq protein
- NP_001123199.1, NP_001123200.1, NP_001123201.1, NP_001123203.1, XP_011521287.1
The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
pleckstrin homology and RhoGEF domain containing G4
- Symbol
- PLEKHG4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:67,277,510-67,289,499
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 18516
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/25894
- genomic end
- 67323402
- genomic start
- 67311413
- chromosome
- human chromosome 16
- cytogenetic location
- 16q22.1
- expressed in
- lactiferous duct
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Puratrophin-1 is a protein that in humans is encoded by the PLEKHG4 gene.
==References==
Excerpted from Wikipedia’s “PLEKHG4” article, available under the CC BY-SA 4.0 licence.