POLB

Name

DNA polymerase beta

Type

protein-coding

Position

42,338,454–42,371,808 (+)

Ensembl

ENSG00000070501

RefSeq RNA

NM_002690.3, XM_005273535.5, XM_005273536.5, XM_005273537.5, XM_005273538.3

RefSeq protein

NP_002681.1, XP_005273592.1, XP_005273593.1, XP_005273594.1, XP_005273595.1

The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011].