PPIH
Sign in to saveAlso known as CYP-20, CYPH, SnuCyp-20, USA-CYP, peptidylprolyl isomerase H
Peptidyl-prolyl cis-trans isomerase H is an enzyme that in humans is encoded by the PPIH gene.
Gene data
PPIH- Name
- peptidylprolyl isomerase H
- Type
- protein-coding
- Aliases
- CYP-20, CYPH, SnuCyp-20, USA-CYP
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
peptidylprolyl isomerase H
- Symbol
- PPIH
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:42,658,185-42,676,758
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein PPIH PDB 1mzw.png
Show 6 more facts
- HomoloGene ID
- 38172
- exact match
- identifiers.org/ncbigene/10465
- genomic start
- 42658335
- genomic end
- 111901091
- cytogenetic location
- 1p34.2
- Commons category
- Peptidyl-prolyl cis-trans isomerase H
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Peptidyl-prolyl cis-trans isomerase H is an enzyme that in humans is encoded by the PPIH gene.
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.