PPRC1
Sign in to saveAlso known as PRC, peroxisome proliferator-activated receptor gamma, coactivator-related 1, PPARG related coactivator 1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 is a protein that in humans is encoded by the PPRC1 gene.
Gene data
PPRC1- Name
- PPARG related coactivator 1
- Type
- protein-coding
- Aliases
- PRC
The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
via MyGene.info
Gene · Ensembl
PPARG related coactivator 1
- Symbol
- PPRC1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:102,132,994-102,150,333
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9006
- exact match
- identifiers.org/ncbigene/23082
- genomic end
- 102150333
- genomic start
- 103892787
- cytogenetic location
- 10q24.32
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 is a protein that in humans is encoded by the PPRC1 gene.
The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals.