PPP3CA

Name

protein phosphatase 3 catalytic subunit alpha

Type

protein-coding

Position

101,023,409–101,348,278 (−)

Aliases

ACCIID, CALN, CALNA, CALNA1, CNA1, DEE91, IECEE, IECEE1, PPP2B

Ensembl

ENSG00000138814

RefSeq RNA

NM_000944.5, NM_001130691.2, NM_001130692.2

RefSeq protein

NP_000935.1, NP_001124163.1, NP_001124164.1

Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]

via MyGene.info

Gene · Ensembl

protein phosphatase 3 catalytic subunit alpha

Symbol

PPP3CA

Biotype

Protein coding

Organism

Homo sapiens

Location

4:101,023,409-101,348,278

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein PPP3CA PDB 1aui.png

via Wikidata · CC0