PPP2R5D
Sign in to saveAlso known as B56D, MRD35, protein phosphatase 2 regulatory subunit B'delta, B56delta
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform is an enzyme that in humans is encoded by the PPP2R5D gene. Mutations in PPP2R5D cause Jordan's syndrome.
In the Vinony graph
Within Vinony's link graph, PPP2R5D is referenced by 8 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Its subject is documented across 4 Wikipedia language editions.
Gene data
PPP2R5D- Name
- protein phosphatase 2 regulatory subunit B'delta
- Type
- protein-coding
- Position
- 42,984,533–43,012,346 (+)
- Aliases
- B56D, B56delta, HJS1, MRD35
- Ensembl
- ENSG00000112640
- RefSeq RNA
- NM_001270476.2, NM_006245.4, NM_180976.3, NM_180977.3
- RefSeq protein
- NP_001257405.1, NP_006236.1, NP_851307.1, NP_851308.1
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
protein phosphatase 2 regulatory subunit B'delta
- Symbol
- PPP2R5D
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:42,984,533-43,012,346
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PPP2R5D PDB 2jak.png
Show 8 more facts
- HomoloGene ID
- 37661
- genomic start
- 42984553
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5528
- genomic end
- 42980080
- chromosome
- human chromosome 6
- cytogenetic location
- 6p21.1
- Commons category
- PPP2R5D
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform is an enzyme that in humans is encoded by the PPP2R5D gene. Mutations in PPP2R5D cause Jordan's syndrome.
== Function == The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Excerpted from Wikipedia’s “PPP2R5D” article, available under the CC BY-SA 4.0 licence.