PPM1B

Also known as PP2C-beta, PP2C-beta-X, PP2CB, PP2CBETA, PPC2BETAX, protein phosphatase, Mg2+/Mn2+ dependent 1B

Protein phosphatase 1B is an enzyme that in humans is encoded by the PPM1B gene.

In the Vinony graph

Vinony's link graph records 8 inbound references to PPM1B, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 2.

Vinony links it to 5 Wikipedia language editions.

Gene data

PPM1B

Name: protein phosphatase, Mg2+/Mn2+ dependent 1B
Type: protein-coding
Aliases: PP2C-beta, PP2C-beta-X, PP2CB, PP2CBETA, PPC2BETAX

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008].

via MyGene.info