PRB3

Also known as G1, PRG, proline-rich protein BstNI subfamily 3, proline rich protein BstNI subfamily 3

Basic salivary proline-rich protein 3 is a protein that in humans is encoded by the PRB3 gene.

Gene data

PRB3

Name: proline rich protein BstNI subfamily 3
Type: protein-coding
Aliases: G1, PRG

This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the 'Long' allele. The protein isoforms encoded by this gene are recognized as the 'first line of oral defense' against the detrimental effects of polyphenols in the diet and pathogen infections. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Nov 2015].

via MyGene.info

Gene · Ensembl

proline rich protein BstNI subfamily 3

Symbol: PRB3
Biotype: Protein coding
Organism: Homo sapiens
Location: 12:11,265,914-11,269,910
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

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HomoloGene ID: 133260
exact match: identifiers.org/ncbigene/5544
genomic start: 11265914
genomic end: 11269707
cytogenetic location: 12p13.2

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Basic salivary proline-rich protein 3 is a protein that in humans is encoded by the PRB3 gene.

The protein encoded by this gene is a proline-rich salivary protein. It is a major constituent of parotid saliva. This protein is proposed to act as a bacterial receptor. This gene and five other genes that also encode salivary proline-rich proteins (PRPs), as well as a gene encoding a lacrimal gland PRP, form a PRP gene cluster in the chromosomal 12p13 region.