Also known as progestagen, gestagen
Progestogens, also sometimes written progestins, progestagens or gestagens, are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). Progesterone is the major and most important progestogen in the body. The progestogens are named for their function in maintaining pregnancy (i.e., progestational), although they are also present at other phases of the estrous and menstrual cycles.
Key facts
- Drug class.Image
- File:Progesterone.svg
- Drug class.ImageClass
- skin-invert-image
- Drug class.Caption
- Progesterone, the major progestogen in humans and a widely used medication.
- Drug class.Width
- 225px
- Drug class.Synonyms
- Progestins; Progestagens; Gestagens,
- Drug class.Use
- Contraception, menopause, hypogonadism, transgender women, others
- Drug class.MeshID
- D011372
- Drug class.ATC_prefix
- G03D
- Drug class.Biological_target
- Progesterone receptors (PRA, PRB, PRC, mPRs (e.g., mPRα, mPRβ, mPRγ, mPRδ, others))
via Wikipedia infobox
Clinical Trials
153 registered- PHASE3COMPLETEDComparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical LengthNational University of Malaysia · NCT04342585
- NACOMPLETEDEffect of Two Different Dosages of Ethinyl-estradiol in Association With Drospirenone in Women With Polycystic Ovary Syndrome.Catholic University of the Sacred Heart · NCT01519401
- COMPLETEDTreatment Regimen in Menstrual Cycle Regularization and Persistence in Routine Clinical Practice in Russia, Ukraine, Kazakhstan and UzbekistanAbbott · NCT01711216
- ACTIVE_NOT_RECRUITINGImpact of Progestin-only Contraception on Bleeding Patterns in Individuals Initiating GATTUniversity of California, San Diego · NCT06230770
- PHASE1COMPLETEDThe Effect of an Adhesive Overlay on the Delivery of Contraceptive Hormones From ORTHO EVRA® in Healthy WomenJohnson & Johnson Pharmaceutical Research & Development, L.L.C. · NCT01535820
- PHASE2/PHASE3RECRUITINGGnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia PatientsXiaojun Chen · NCT05316935
Wikidata facts
- Instance of
- steroid hormone
- Subclass of
- sex steroid
- Image
- Progesterone.svg
Show 4 more facts
- facet of
- women's health
- Commons category
- Progestagens
- topic's main category
- Category:Progestogens
- NCI Thesaurus ID
- C2296
Sources (3)
via Wikidata · CC0
Article · 中文
孕激素(英語:progestogens)是一群具有诱发孕前子宫变化和维持妊娠功能的类固醇激素,包括天然的和人工合成的化合物,最主要的激素为孕酮,主要来源于卵巢的黄体细胞(luteal cells),且是雌激素和雄激素的共同前体。 所有孕激素都有着基于二十一个碳骨架的特征,这种骨架叫做孕甾烷骨架(C21)。与此骨架类比,雌激素具有雌烷骨架(C18),而雄激素具有雄烷骨架(C19)。 孕激素是五大类类固醇激素中的一大类,其他四种分别是雌激素、雄激素、盐皮质激素与糖皮质激素。
Abstract from DBpedia / Wikipedia · CC BY-SA
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