Structure via PubChem · Public domain (PubChem)
propanidid
Sign in to savePropanidid is an ultra short-acting phenylacetate general anesthetic. It was originally introduced by Bayer in 1963 but anaphylactic reactions caused it to be withdrawn shortly afterwards.
Chemical data
- Formula
- C18H27NO5
- Molecular weight
- 337.4 g/mol
- IUPAC name
- propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate
- SMILES
- CCCOC(=O)CC1=CC(=C(C=C1)OCC(=O)N(CC)CC)OC
- InChIKey
- KEJXLQUPYHWCNM-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 65.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,000 papers- Propanidid.British journal of anaesthesia · 1970
- The eugenols--propanidid.International anesthesiology clinics · 1969
- Intravenous Induction Agents--propanidid.Anaesthesia and intensive care · 2002
- Propanidid in anaesthesia.The Medical journal of Australia · 1970
- Propanidid in epilepsy.Anaesthesia · 1974
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 337.189
Show 3 more facts
- chemical formula
- C₁₈H₂₇NO₅
- canonical SMILES
- CCCOC(=O)CC1=CC(=C(C=C1)OCC(=O)N(CC)CC)OC
- Commons category
- Propanidid
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464216117 | IUPAC_name = Propyl {4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl}acetate | image = Propanidid.svg | image_class = skin-invert-image | width = 200
| tradename = Epontol | Drugs.com = | pregnancy_category = | legal_AU = | legal_BR = C1 | legal_BR_comment = | legal_CA = | legal_DE = | legal_NZ = | legal_UK = | legal_US = | legal_EU = | legal_UN = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “propanidid” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0