Structure via PubChem · Public domain (PubChem)
Also known as 1,2-Diazole, Hpz, 1H-Pyrazol, Pyrazole
Pyrazole is an organic compound with the formula . It is a heterocycle characterized as an azole with a 5-membered ring of three carbon atoms and two adjacent nitrogen atoms, which are in ortho-substitution. Pyrazoles are also a class of compounds that have the ring C3N2 with adjacent nitrogen atoms. Pyrazole itself has few applications but many substituted pyrazoles are of commercial interest. Notable drugs containing a pyrazole ring are celecoxib (celebrex) and the anabolic steroid stanozolol.
In the Vinony graph
Vinony's link graph records 137 inbound references to 피라졸, and connects out to carbon, watermelon and International Standard Book Number.
It sits within the topics Aromatic bases, Chembox having GHS data and ECHA InfoCard ID from Wikidata.
Vinony links it to 30 Wikipedia language editions.
Chemical data
- Formula
- C3H4N2
- Molecular weight
- 68.08 g/mol
- IUPAC name
- 1H-pyrazole
- SMILES
- C1=CNN=C1
- InChIKey
- WTKZEGDFNFYCGP-UHFFFAOYSA-N
- XLogP
- 0.3
- Polar surface area
- 28.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
76,074 papers- Pyrazole: an emerging privileged scaffold in drug discovery.Future medicinal chemistry · 2023
- Pyrazole Paradigms: Unveiling Synthetic Pathways and Unraveling Anti-Cancer Potential.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2024
- Pyrazole, Pyrazoline, and Fused Pyrazole Derivatives: New Horizons in EGFR-Targeted Anticancer Agents.Chemistry & biodiversity · 2024
- Pyrazole-based analogs as potential antibacterial agents against methicillin-resistance staphylococcus aureus (MRSA) and its SAR elucidation.European journal of medicinal chemistry · 2021
- Pyrazole Scaffold Synthesis, Functionalization, and Applications in Alzheimer's Disease and Parkinson's Disease Treatment (2011-2020).Molecules (Basel, Switzerland) · 2021
via PubMed
Wikidata facts
- Subclass of
- heterocyclic compound
- Has part
- carbon
- Mass
- 68.037
Show 9 more facts
- described by source
- Encyclopædia Britannica 11th edition
- Commons category
- Pyrazole
- chemical formula
- C₃H₄N₂
- canonical SMILES
- C1=CNN=C1
- subject has role
- enzyme inhibitor
- boiling point
- 187
- melting point
- 68
- found in taxon
- liquorice
- has characteristic
- bitterness
via Wikidata · CC0