pyrithyldione
Sign in to savePyrithyldione (Presidon, Persedon) is a psychoactive drug invented in 1949. An improved method of manufacture was patented by Roche in 1959. It was used as a hypnotic or sedative and presumed to be less toxic than barbiturates. Today, this substance is no longer used. Agranulocytosis was sometimes reported as adverse effect. Pyrithyldione is also a CYP2D6 inducer but is not as potent as glutethimide. In studies, it increased the O-demethylation of codeine by 20%.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 167.095
Show 3 more facts
- chemical formula
- C₉H₁₃NO₂
- canonical SMILES
- CCC1(C(=O)C=CNC1=O)CC
- Commons category
- Pyrithyldione
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Encyclopedic overview
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Pyrithyldione (Presidon, Persedon) is a psychoactive drug invented in 1949. An improved method of manufacture was patented by Roche in 1959. It was used as a hypnotic or sedative and presumed to be less toxic than barbiturates. Today, this substance is no longer used. Agranulocytosis was sometimes reported as adverse effect. Pyrithyldione is also a CYP2D6 inducer but is not as potent as glutethimide. In studies, it increased the O-demethylation of codeine by 20%.
== See also == Methyprylon Piperidione Glutethimide
Excerpted from Wikipedia’s “pyrithyldione” article, available under the CC BY-SA 4.0 licence.