RAD54B
Sign in to saveAlso known as RDH54, RAD54 homolog B (S. cerevisiae), RAD54 homolog B
DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene.
In the Vinony graph
Within Vinony's link graph, RAD54B is referenced by 7 other articles, and connects out to PubMed, human chromosome 8 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 8.
Its subject is documented across 5 Wikipedia language editions.
Gene data
RAD54B- Name
- RAD54 homolog B
- Type
- protein-coding
- Aliases
- RDH54
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
RAD54 homolog B
- Symbol
- RAD54B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:94,371,960-94,475,134
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8240
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/25788
- cytogenetic location
- 8q22.1
- chromosome
- human chromosome 8
- genomic start
- 95384188
- genomic end
- 94475115
Sources (4)
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- Cancer
- References
- Further reading
DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene.
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Excerpted from Wikipedia’s “RAD54B” article, available under the CC BY-SA 4.0 licence.