RCC2

Also known as TD-60, regulator of chromosome condensation 2

Protein RCC2 also known as telophase disk protein of 60 kDa (TD-60) or RCC1-like protein TD-60 is a protein that in humans is encoded by the RCC2 gene.

Gene data

RCC2

Name: regulator of chromosome condensation 2
Type: protein-coding
Position: 17,406,755–17,439,772 (−)
Aliases: TD-60
Ensembl: ENSG00000281540
RefSeq RNA: NM_001136204.3, NM_018715.4
RefSeq protein: NP_001129676.1, NP_061185.1

The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer. [provided by RefSeq, Oct 2016].

Gene Ontology

Biological process

integrin-mediated signaling pathway regulation of fibroblast migration positive regulation of G2/M transition of mitotic cell cycle

Article

4 sections

Contents

Function
References
Further reading
External links

Protein RCC2 also known as telophase disk protein of 60 kDa (TD-60) or RCC1-like protein TD-60 is a protein that in humans is encoded by the RCC2 gene.

== Function ==