
(RS)-methylone
Sign in to saveAlso known as MDMC, βk-MDMA, 3,4-methylenedioxy-N-methylcathinone
Methylone, also known as '3,4-methylenedioxy-N-methylcathinone (MDMC'), is an entactogen and stimulant drug of the amphetamine, cathinone, and MDxx families related to 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"). It is the β-keto or cathinone analogue of MDMA. The drug is usually taken orally, but can also be administered by other routes.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 457117430
- Drug.image
- Methylone structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 235px
- Drug.image2
- MDMC-3d-sticks.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250px
- Drug.routes_of_administration
- Common: oral, insufflationUncommon: IV or IM injection, rectal
- Drug.class
- Serotonin–norepinephrine–dopamine releasing agent; Entactogen
- Drug.ATC_prefix
- None
- Drug.legal_AU
- Unscheduled
- Drug.legal_BR
- F2
- Drug.legal_CA
- Schedule I
- Drug.legal_UK
- Class B
- Drug.legal_US
- Schedule I
- Drug.legal_DE
- Anlage II
via Wikipedia infobox
Wikidata facts
- Mass
- 207.09
Show 3 more facts
- canonical SMILES
- CC(C(=O)C1=CC2=C(C=C1)OCO2)NC
- chemical formula
- C₁₁H₁₃NO₃
- Commons category
- Methylone
Sources (2)
via Wikidata · CC0
~16 min read
Article
23 sectionsContents
- Use and effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Synthesis
- History
- Society and culture
- Names and etymology
- Commercial distribution
- Legal status
- Netherlands
- New Zealand
- United Kingdom
- Sweden
- Canada
- United States
- Research
- Post-traumatic stress disorder
- See also
- References
- External links
Methylone, also known as '3,4-methylenedioxy-N-methylcathinone (MDMC'), is an entactogen and stimulant drug of the amphetamine, cathinone, and MDxx families related to 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"). It is the β-keto or cathinone analogue of MDMA. The drug is usually taken orally, but can also be administered by other routes.
It acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA). The drug has much less activity at the vesicular monoamine transporter 2 (VMAT2) than MDMA and may have less serotonergic neurotoxicity. In contrast to certain other entactogens like MDMA, methylone does not appear to be a significant agonist of the serotonin 5-HT2 receptors. Methylone is similar in its effects to MDMA, producing entactogenic effects and euphoria, but has a reputation of being gentler than MDMA and only lasts about half as long. Side effects of methylone include tachycardia, hangover, and insomnia. It may have reduced negative after-effects compared to MDMA. Methylone's onset is about 0.5hours and its duration is about 2 to 3hours.