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(RS)-methylone
EntityQ4046265· pop 19· linked from 2,788 articles

(RS)-methylone

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Also known as MDMC, βk-MDMA, 3,4-methylenedioxy-N-methylcathinone

Methylone, also known as '3,4-methylenedioxy-N-methylcathinone (MDMC'), is an entactogen and stimulant drug of the amphetamine, cathinone, and MDxx families related to 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"). It is the β-keto or cathinone analogue of MDMA. The drug is usually taken orally, but can also be administered by other routes.

Key facts

Drug.Verifiedfields
changed
Drug.Watchedfields
changed
Drug.verifiedrevid
457117430
Drug.image
Methylone structure.svg
Drug.image_class
skin-invert-image
Drug.width
235px
Drug.image2
MDMC-3d-sticks.png
Drug.image_class2
bg-transparent
Drug.width2
250px
Drug.routes_of_administration
Common: oral, insufflationUncommon: IV or IM injection, rectal
Drug.class
Serotonin–norepinephrine–dopamine releasing agent; Entactogen
Drug.ATC_prefix
None
Drug.legal_AU
Unscheduled
Drug.legal_BR
F2
Drug.legal_CA
Schedule I
Drug.legal_UK
Class B
Drug.legal_US
Schedule I
Drug.legal_DE
Anlage II

via Wikipedia infobox

Wikidata facts

Mass
207.09
Show 3 more facts
canonical SMILES
CC(C(=O)C1=CC2=C(C=C1)OCO2)NC
chemical formula
C₁₁H₁₃NO₃
Commons category
Methylone
Sources (2)

via Wikidata · CC0

~16 min read

Article

23 sections
Contents
  • Use and effects
  • Interactions
  • Pharmacology
  • Pharmacodynamics
  • Pharmacokinetics
  • Chemistry
  • Synthesis
  • History
  • Society and culture
  • Names and etymology
  • Commercial distribution
  • Legal status
  • Netherlands
  • New Zealand
  • United Kingdom
  • Sweden
  • Canada
  • United States
  • Research
  • Post-traumatic stress disorder
  • See also
  • References
  • External links

Methylone, also known as '3,4-methylenedioxy-N-methylcathinone (MDMC'), is an entactogen and stimulant drug of the amphetamine, cathinone, and MDxx families related to 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"). It is the β-keto or cathinone analogue of MDMA. The drug is usually taken orally, but can also be administered by other routes.

It acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA). The drug has much less activity at the vesicular monoamine transporter 2 (VMAT2) than MDMA and may have less serotonergic neurotoxicity. In contrast to certain other entactogens like MDMA, methylone does not appear to be a significant agonist of the serotonin 5-HT2 receptors. Methylone is similar in its effects to MDMA, producing entactogenic effects and euphoria, but has a reputation of being gentler than MDMA and only lasts about half as long. Side effects of methylone include tachycardia, hangover, and insomnia. It may have reduced negative after-effects compared to MDMA. Methylone's onset is about 0.5hours and its duration is about 2 to 3hours.

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