RTN1
Sign in to saveAlso known as NSP, reticulon 1
Reticulon-1 also known as neuroendocrine-specific protein (NSP) is a protein that in humans is encoded by the RTN1 gene.
In the Vinony graph
Vinony's link graph records 6 inbound references to RTN1, and connects out to PubMed, human chromosome 14 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 14.
Vinony links it to 5 Wikipedia language editions.
Gene data
RTN1- Name
- reticulon 1
- Type
- protein-coding
- Position
- 59,595,976–59,870,850 (−)
- Aliases
- NSP
- Ensembl
- ENSG00000139970
- RefSeq RNA
- NM_001243115.1, NM_001363702.1, NM_021136.3, NM_206852.3, NM_206857.1
- RefSeq protein
- NP_001350631.1, NP_066959.1, NP_996734.1, XP_011535365.1, XP_047287630.1
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
reticulon 1
- Symbol
- RTN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:59,595,976-59,870,850
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 49654
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6252
- genomic end
- 59870776
- genomic start
- 60062694
- chromosome
- human chromosome 14
- cytogenetic location
- 14q23.1
- expressed in
- parietal lobe
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Reticulon-1 also known as neuroendocrine-specific protein (NSP) is a protein that in humans is encoded by the RTN1 gene.
This gene belongs to the family of reticulon-encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified. Multiple promoters rather than alternative splicing of internal exons seem to be involved in this diversity.
Excerpted from Wikipedia’s “RTN1” article, available under the CC BY-SA 4.0 licence.