RTN2
Sign in to saveAlso known as NSP2, NSPL1, NSPLI, SPG12, reticulon 2
Reticulon-2 is a protein that in humans is encoded by the RTN2 gene.
Gene data
RTN2- Name
- reticulon 2
- Type
- protein-coding
- Aliases
- HMNR11, NSP2, NSPL1, NSPLI, SPG12
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Reticulon proteins also play an important role in the replication of positive-strand RNA (ssRNA) viruses. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Aug 2020].
via MyGene.info
Gene · Ensembl
reticulon 2
- Symbol
- RTN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:45,485,292-45,497,055
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 32180
- exact match
- identifiers.org/ncbigene/6253
- genomic end
- 45497055
- genomic start
- 45485294
- cytogenetic location
- 19q13.32
Sources (3)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Reticulon-2 is a protein that in humans is encoded by the RTN2 gene.
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified.