RTN2
Sign in to saveAlso known as NSP2, NSPL1, NSPLI, SPG12, reticulon 2
Reticulon-2 is a protein that in humans is encoded by the RTN2 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to RTN2, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Vinony links it to 5 Wikipedia language editions.
Gene data
RTN2- Name
- reticulon 2
- Type
- protein-coding
- Position
- 45,485,292–45,497,055 (−)
- Aliases
- HMNR11, NSP2, NSPL1, NSPLI, SPG12
- Ensembl
- ENSG00000125744
- RefSeq RNA
- NM_001445029.1, NM_001445030.1, NM_001445031.1, NM_001445032.1, NM_001445033.1
- RefSeq protein
- NP_001431958.1, NP_001431959.1, NP_001431960.1, NP_001431961.1, NP_001431962.1
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Reticulon proteins also play an important role in the replication of positive-strand RNA (ssRNA) viruses. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Aug 2020].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
reticulon 2
- Symbol
- RTN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:45,485,292-45,497,055
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 32180
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6253
- genomic end
- 45497055
- genomic start
- 45485294
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.32
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Reticulon-2 is a protein that in humans is encoded by the RTN2 gene.
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Excerpted from Wikipedia’s “RTN2” article, available under the CC BY-SA 4.0 licence.