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S-18986
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S-18986 is a positive allosteric modulator of the AMPA receptor related to cyclothiazide. It has nootropic and neuroprotective effects in animal studies, and induces both production of BDNF and AMPA-mediated release of noradrenaline and acetylcholine in the hippocampus and frontal cortex of the brain.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 224.061949
Show 3 more facts
- chemical formula
- C₁₀H₁₂N₂O₂S
- isomeric SMILES
- C1C[C@@H]2NS(=O)(=O)C3=CC=CC=C3N2C1
- canonical SMILES
- C1CC2NS(=O)(=O)C3=CC=CC=C3N2C1
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Encyclopedic overview
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- See also
- References
S-18986 is a positive allosteric modulator of the AMPA receptor related to cyclothiazide. It has nootropic and neuroprotective effects in animal studies, and induces both production of BDNF and AMPA-mediated release of noradrenaline and acetylcholine in the hippocampus and frontal cortex of the brain.
==See also== AMPA receptor positive allosteric modulator
Excerpted from Wikipedia’s “S-18986” article, available under the CC BY-SA 4.0 licence.