SERINC3

Also known as AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1, serine incorporator 3

Serine incorporator 3 is a protein that in humans is encoded by the SERINC3 gene. It has been demonstrated that SERINC3 acts as a retrovirus restriction factor.

In the Vinony graph

Vinony's link graph records 2 inbound references to SERINC3, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 20.

Vinony links it to 6 Wikipedia language editions.

Gene data

SERINC3

Name: serine incorporator 3
Type: protein-coding
Position: 44,494,494–44,522,110 (−)
Aliases: AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1
Ensembl: ENSG00000132824
RefSeq RNA: NM_006811.4, NM_198941.3
RefSeq protein: NP_006802.1, NP_945179.1

Predicted to enable L-serine transmembrane transporter activity. Involved in defense response to virus; detection of virus; and innate immune response. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

plasma membrane phospholipid scrambling antiviral innate immune response

Molecular function

protein binding phospholipid scramblase activity molecular carrier activity

Cellular component

Golgi membrane Golgi membrane Golgi apparatus plasma membrane plasma membrane plasma membrane membrane membrane

Pathways

Metabolism Metabolism of amino acids and derivatives Serine metabolism

via MyGene.info

Gene · Ensembl

serine incorporator 3

Symbol: SERINC3
Biotype: Protein coding
Organism: Homo sapiens
Location: 20:44,494,494-44,522,110
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 38230
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/10955
genomic end: 44522085
genomic start: 43124862
chromosome: human chromosome 20
cytogenetic location: 20q13.12
expressed in: prefrontal cortex

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Serine incorporator 3 is a protein that in humans is encoded by the SERINC3 gene. It has been demonstrated that SERINC3 acts as a retrovirus restriction factor.

== References ==

Excerpted from Wikipedia’s “SERINC3” article, available under the CC BY-SA 4.0 licence.