SERPINA3
Sign in to saveAlso known as AACT, ACT, GIG24, GIG25, serpin family A member 3
protein-coding gene in the species Homo sapiens
Gene data
SERPINA3- Name
- serpin family A member 3
- Type
- protein-coding
- Position
- 94,612,377–94,624,645 (+)
- Aliases
- AACT, ACT, GIG24, GIG25
- Ensembl
- ENSG00000196136
- RefSeq RNA
- NM_001085.5, NM_001384672.1, NM_001384673.1, NM_001384674.1
- RefSeq protein
- NP_001076.2, NP_001371601.1, NP_001371602.1, NP_001371603.1
The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jun 2020].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
serpin family A member 3
- Symbol
- SERPINA3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:94,598,861-94,627,000
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- PBB Protein SERPINA3 image.jpg
Show 6 more facts
- HomoloGene ID
- 111129
- exact match
- identifiers.org/ncbigene/12
- genomic start
- 94612384
- genomic end
- 94624055
- cytogenetic location
- 14q32.13
- Commons category
- Alpha 1-antichymotrypsin
Sources (4)
via Wikidata · CC0