SERPIND1

Also known as D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10, serpin family D member 1

protein-coding gene in the species Homo sapiens

Gene data

SERPIND1

Name: serpin family D member 1
Type: protein-coding
Aliases: D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10

This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015].

via MyGene.info