SLC2A5
Sign in to saveAlso known as GLUT-5, GLUT5, solute carrier family 2 member 5
GLUT5 is a fructose transporter expressed on the apical border of enterocytes in the small intestine. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue (adipocytes), and brain.
In the Vinony graph
Vinony's link graph records 356 inbound references to SLC2A5, and connects out to PubMed, enterocyte and Ensembl genome database project.
Vinony files it under Genes on human chromosome 1 and Solute carrier family.
Vinony links it to 9 Wikipedia language editions.
Gene data
SLC2A5- Name
- solute carrier family 2 member 5
- Type
- protein-coding
- Position
- 9,035,106–9,088,478 (−)
- Aliases
- GLUT-5, GLUT5
- Ensembl
- ENSG00000142583
- RefSeq RNA
- NM_001135585.2, NM_001328619.2, NM_001328620.2, NM_001328621.2, NM_003039.3
- RefSeq protein
- NP_001129057.1, NP_001315548.1, NP_001315549.1, NP_001315550.1, NP_003030.1
The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
solute carrier family 2 member 5
- Symbol
- SLC2A5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:9,035,106-9,088,478
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- GLUT5.png
Show 9 more facts
- HomoloGene ID
- 74459
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6518
- chromosome
- human chromosome 1
- genomic start
- 9035106
- genomic end
- 9148537
- cytogenetic location
- 1p36.23
- expressed in
- bone marrow
- Commons category
- Glucose transporter 5
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Regulation
- Interactive pathway map
- References
- External links
GLUT5 is a fructose transporter expressed on the apical border of enterocytes in the small intestine. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue (adipocytes), and brain.
Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient.
Excerpted from Wikipedia’s “SLC2A5” article, available under the CC BY-SA 4.0 licence.