GPR35
Sign in to saveAlso known as G protein-coupled receptor 35
G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.
In the Vinony graph
Within Vinony's link graph, GPR35 is referenced by 493 other articles, and connects out to PubMed, Ensembl genome database project and sequence homology.
It is catalogued under topics including Genes on human chromosome 2 and G protein-coupled receptors.
Its subject is documented across 5 Wikipedia language editions.
Gene data
GPR35- Name
- G protein-coupled receptor 35
- Type
- protein-coding
- Position
- 240,605,404–240,633,159 (+)
- Ensembl
- ENSG00000178623
- RefSeq RNA
- NM_001195381.3, NM_001195382.3, NM_001394730.1, NM_005301.5
- RefSeq protein
- NP_001182310.1, NP_001182311.1, NP_001381659.1, NP_005292.2
Enables C-X-C chemokine receptor activity. Involved in several processes, including chemokine-mediated signaling pathway; negative regulation of voltage-gated calcium channel activity; and positive regulation of cytosolic calcium ion concentration. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
G protein-coupled receptor 35
- Symbol
- GPR35
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:240,605,404-240,633,159
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 3874
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2859
- genomic start
- 240605430
- chromosome
- human chromosome 2
- genomic end
- 240633159
- cytogenetic location
- 2q37.3
via Wikidata · CC0
~2 min read
Encyclopedic overview
6 sectionsContents
- Ligands
- Endogenous ligands
- Synthetic agonists
- Antagonists
- Clinical significance
- References
G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.
== Ligands ==
Excerpted from Wikipedia’s “GPR35” article, available under the CC BY-SA 4.0 licence.