streptogramins
Sign in to saveAlso known as streptogramin
class=skin-invert-image|thumb|Pristinamycin IA, a natural member of the streptogramin B class class=skin-invert-image|thumb|Pristinamycin IIA, a natural member of the streptogramin A class Streptogramins are a class of antibiotics. They work as protein synthesis inhibitors.
Research
2,937 papers- Streptogramins for the treatment of infections caused by Gram-positive pathogens.Expert review of anti-infective therapy · 2021
- Streptogramins - two are better than one!International journal of medical microbiology : IJMM · 2014
- Consumption of macrolides, lincosamides and streptogramins in the community, European Union/European Economic Area, 1997-2017.The Journal of antimicrobial chemotherapy · 2021
- Streptogramins. A unique class of antibiotics.Drugs · 1996
- Lincosamides, Streptogramins, Phenicols, and Pleuromutilins: Mode of Action and Mechanisms of Resistance.Cold Spring Harbor perspectives in medicine · 2016
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class=skin-invert-image|thumb|Pristinamycin IA, a natural member of the streptogramin B class class=skin-invert-image|thumb|Pristinamycin IIA, a natural member of the streptogramin A class Streptogramins are a class of antibiotics. They work as protein synthesis inhibitors.
Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus aureus (VRSA) and vancomycin-resistant Enterococcus (VRE), two of the most rapidly growing strains of multidrug-resistant bacteria. They fall into two groups: streptogramin A (23-membered macrolide) and streptogramin B (depsipeptide). The two groups act synergistically. They are naturally produced in a 3:7 ratio; most formulations keep this ratio.