STXBP5

Name

syntaxin binding protein 5

Type

protein-coding

Position

147,203,502–147,391,010 (+)

Aliases

LGL3, LLGL3, Nbla04300

Ensembl

ENSG00000164506

RefSeq RNA

NM_001127715.4, NM_001394409.1, NM_139244.6, XM_017010268.3, XM_047418197.1

RefSeq protein

NP_001121187.1, NP_001381338.1, NP_640337.3, XP_016865757.1, XP_047274153.1

Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

syntaxin binding protein 5

Symbol

STXBP5

Biotype

Protein coding

Organism

Homo sapiens

Location

6:147,203,502-147,391,010

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein STXBP5 PDB 1urq.png

via Wikidata · CC0