terguride
Sign in to saveAlso known as dironyl
Terguride (, ), sold under the brand name Teluron, is a serotonin receptor antagonist and dopamine receptor agonist of the ergoline family. It is approved for and used as a prolactin inhibitor in the treatment of hyperprolactinemia (high prolactin levels) in Japan. Terguride is taken by mouth.
Research
215 papers- Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats.The European respiratory journal · 2011
- Blocking properties of terguride at the 5-HT(2) receptor subtypes mediating cardiovascular responses in the rat.Canadian journal of physiology and pharmacology · 2020
- Antiserotonergic properties of terguride in blood vessels, platelets, and valvular interstitial cells.The Journal of pharmacology and experimental therapeutics · 2012
- Terguride for dyskinesias.Neurology · 1993
- Terguride as a new anti-hyperprolactinemic agent: characterization in rats and dogs in comparison with bromocriptine.Japanese journal of pharmacology · 1993
via PubMed
Wikidata facts
- Mass
- 340.226312
Show 3 more facts
- chemical formula
- C₂₀H₂₈N₄O
- isomeric SMILES
- CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)C
- canonical SMILES
- CCN(CC)C(=O)NC1CC2C(CC3=CNC4=CC=CC2=C34)N(C1)C
Sources (2)
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Article
5 sectionsContents
- Pharmacology
- Pharmacodynamics
- Research
- See also
- References
Terguride (, ), sold under the brand name Teluron, is a serotonin receptor antagonist and dopamine receptor agonist of the ergoline family. It is approved for and used as a prolactin inhibitor in the treatment of hyperprolactinemia (high prolactin levels) in Japan. Terguride is taken by mouth.
==Pharmacology==
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