Also known as TGFB induced factor homeobox 2
Homeobox protein TGIF2 is a protein that in humans is encoded by the TGIF2 gene.
The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010].
via MyGene.info
Homeobox protein TGIF2 is a protein that in humans is encoded by the TGIF2 gene.
The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor. The encoded protein appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).