Structure via PubChem · Public domain (PubChem)
theaflavin
Sign in to saveTheaflavin (TF) and its derivatives, known collectively as theaflavins, are antioxidant polyphenols that are formed from the condensation of flavan-3-ols in tea leaves during the enzymatic oxidation (sometimes erroneously referred to as fermentation) of black tea. Theaflavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3-3'-digallate are the main theaflavins. Theaflavins are types of thearubigins, and are therefore reddish in color.
In the Vinony graph
Within Vinony's link graph, theaflavin is referenced by 244 other articles, and connects out to Chinese tea culture, tea processing and Phenolic content in tea.
It is catalogued under topics including Antiviral drugs, Catechols and Chembox image size set.
Its subject is documented across 14 Wikipedia language editions.
Chemical data
- Formula
- C29H24O12
- Molecular weight
- 564.5 g/mol
- IUPAC name
- 3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]benzo[7]annulen-6-one
- SMILES
- C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=O)C(=C4C(=C3)C(=CC(=C4O)O)[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)O)O)O
- InChIKey
- IPMYMEWFZKHGAX-ZKSIBHASSA-N
- XLogP
- 0.6
- Polar surface area
- 218 Ų
- H-bond donors
- 9
- H-bond acceptors
- 12
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,105 papers- Theaflavin Chemistry and Its Health Benefits.Oxidative medicine and cellular longevity · 2021
- Theaflavin suppresses necroptosis by attenuating RIPK1-RIPK3-MLKL signaling and mitigates cisplatin-induced kidney injury in mice.International immunopharmacology · 2025
- Theaflavin reduces Achilles tendon heterotopic ossification in mice through the TGF-β/Smad signaling pathway.Biochemical pharmacology · 2025
- Theaflavin: a natural candidate to restrain thrombosis.Food & function · 2022
- Theaflavin Ameliorates Streptococcus suis-Induced Infection In Vitro and In Vivo.International journal of molecular sciences · 2023
via PubMed
Wikidata facts
- Mass
- 564.127
Show 5 more facts
- isomeric SMILES
- C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=O)C(=C4C(=C3)C(=CC(=C4O)O)[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)O)O)O
- chemical formula
- C₂₉H₂₄O₁₂
- canonical SMILES
- C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=O)C(=C4C(=C3)C(=CC(=C4O)O)C5C(CC6=C(C=C(C=C6O5)O)O)O)O)O
- subject has role
- antioxidant
- Commons category
- Theaflavin
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Theaflavin (TF) and its derivatives, known collectively as theaflavins, are antioxidant polyphenols that are formed from the condensation of flavan-3-ols in tea leaves during the enzymatic oxidation (sometimes erroneously referred to as fermentation) of black tea. Theaflavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3-3'-digallate are the main theaflavins. Theaflavins are types of thearubigins, and are therefore reddish in color.
== See also == Theaflavin 3-gallate
Excerpted from Wikipedia’s “theaflavin” article, available under the CC BY-SA 4.0 licence.