tocofersolan
Sign in to saveAlso known as tocophersolan, TPGS
Tocofersolan (INN; also known as tocophersolan, tocopherol polyethylene glycol succinate, or TPGS) is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is a polyethylene glycol (PEG) derivative of α-tocopherol succinate. The addition of PEG enables water solubility.
Research
723 papers- The use of tocofersolan as a rescue agent in larval zebrafish exposed to benzo[a]pyrene in early development.Neurotoxicology · 2021
- Oral Tocofersolan Corrects or Prevents Vitamin E Deficiency in Children With Chronic Cholestasis.Journal of pediatric gastroenterology and nutrition · 2016
- Efficacy of two vitamin E formulations in patients with abetalipoproteinemia and chylomicron retention disease.Journal of lipid research · 2018
- siRNA-loaded folic acid-modified TPGS alleviate MASH via targeting ER stress sensor XBP1 and reprogramming macrophages.International journal of biological sciences · 2024
- Bioavailability of oral vitamin E formulations in adult volunteers and children with chronic cholestasis or cystic fibrosis.Journal of clinical pharmacy and therapeutics · 2009
via PubMed
Wikidata facts
- Mass
- 574.423339576
Show 3 more facts
- canonical SMILES
- O=C(OCCO)CCC(=O)Oc2c(c(c1OC(CCc1c2C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)C
- chemical formula
- C₃₅H₅₈O₆
- isomeric SMILES
- Cc1c(C)c2c(c(C)c1OC(=O)CCC(=O)OCCO)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2
Sources (2)
via Wikidata · CC0
~2 min read
Article
1 sectionsContents
- References
{{chembox | Verifiedfields = changed | verifiedrevid = 470611287 | Name = | ImageFile = Tocophersolan.png | ImageClass = skin-invert-image | ImageSize = 250px | IUPACName = α-Hydro-ω-{[4-oxo-4-({(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl}oxy)butanoyl]oxy}poly(oxyethylene) | OtherNames = Tocofersolan; Vitamin E PEG succinate; α-Tocopherol polyethylene glycol succinate (TPGS); Liqui-E | SystematicName = | Section1 = | Section2 = | Section3 = | Section4 = | Section5 = | Section6 = | Section7 = }}
Tocofersolan (INN; also known as tocophersolan, tocopherol polyethylene glycol succinate, or TPGS) is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is a polyethylene glycol (PEG) derivative of α-tocopherol succinate. The addition of PEG enables water solubility.
Available in 7 languages
via Wikidata sitelinks · CC0