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GeneQ18048937· pop 6· linked from 3 articles

TOE1

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Also known as hCaf1z, target of EGR1, member 1 (nuclear), PCH7, target of EGR1, exonuclease, TOE-1

Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene.

Gene data

TOE1

Name: target of EGR1, exonuclease
Type: protein-coding
Position: 45,340,012–45,343,976 (+)
Aliases: PCH7, TOE-1, hCaf1z
Ensembl: ENSG00000132773
RefSeq RNA: NM_025077.4, XM_005270412.5, XM_005270413.6, XM_047443500.1, XM_047443504.1
RefSeq protein: NP_079353.3, XP_005270469.1, XP_005270470.1, XP_047299456.1, XP_047299460.1

Enables poly(A)-specific ribonuclease activity and snRNA binding activity. Involved in RNA phosphodiester bond hydrolysis, exonucleolytic and snRNA 3'-end processing. Located in Cajal body and cytoplasm. Implicated in pontocerebellar hypoplasia type 7. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

RNA metabolic process snRNA 3'-end processing snRNA 3'-end processing

Molecular function

3'-5'-RNA exonuclease activity 3'-5'-RNA exonuclease activity nucleic acid binding poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity protein binding snRNA binding snRNA binding

Cellular component

nucleolus cytoplasm Cajal body Cajal body nuclear speck

via MyGene.info

Wikidata facts

Show 5 more facts

HomoloGene ID: 11823
exact match: identifiers.org/ncbigene/114034
genomic end: 45343973
genomic start: 45340052
cytogenetic location: 1p34.1

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Further reading

Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene.

==References==

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Categories

Genes on human chromosome 1