TOE1

Also known as hCaf1z, target of EGR1, member 1 (nuclear), PCH7, target of EGR1, exonuclease, TOE-1

Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene.

Gene data

TOE1

Name: target of EGR1, exonuclease
Type: protein-coding
Position: 45,340,012–45,343,976 (+)
Aliases: PCH7, TOE-1, hCaf1z
Ensembl: ENSG00000132773
RefSeq RNA: NM_025077.4, XM_005270412.5, XM_005270413.6, XM_047443500.1, XM_047443504.1
RefSeq protein: NP_079353.3, XP_005270469.1, XP_005270470.1, XP_047299456.1, XP_047299460.1

Enables poly(A)-specific ribonuclease activity and snRNA binding activity. Involved in RNA phosphodiester bond hydrolysis, exonucleolytic and snRNA 3'-end processing. Located in Cajal body and cytoplasm. Implicated in pontocerebellar hypoplasia type 7. [provided by Alliance of Genome Resources, Apr 2022]