EEF1E1
Sign in to saveAlso known as AIMP3, P18, eukaryotic translation elongation factor 1 epsilon 1
Eukaryotic translation elongation factor 1 epsilon-1 is a protein that in humans is encoded by the EEF1E1 gene.
Gene data
EEF1E1- Name
- eukaryotic translation elongation factor 1 epsilon 1
- Type
- protein-coding
- Aliases
- AIMP3, P18
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010].
via MyGene.info
Gene · Ensembl
eukaryotic translation elongation factor 1 epsilon 1
- Symbol
- EEF1E1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:8,073,259-8,102,625
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 3161
- exact match
- identifiers.org/ncbigene/9521
- genomic start
- 8073593
- genomic end
- 8102559
- cytogenetic location
- 6p24.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- Further reading
- External links
Eukaryotic translation elongation factor 1 epsilon-1 is a protein that in humans is encoded by the EEF1E1 gene.
==References==