trimecaine
Sign in to saveAlso known as mesidicaine, 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide
Trimecaine (systematic name (2,4,6-trimethylphenylcarbamoylmethyl)diethylammonium chloride, chemical formula C15H25ClN2O) is an organic compound used as a local anesthetic and cardial antiarrhythmic. It is white crystalline powder readily soluble in water and ethanol. It is an active ingredient in products available under trademarks Mesdicain, Mesocain, Mesokain and others.
Research
376 papers- [Trimecaine].Meditsinskaia promyshlennost' SSSR · 1962
- Activation of Leukopoiesis in Rat Blood with Trimecaine-Based Ionic Compounds.BioMed research international · 2020
- [Trimecaine identification reactions].Farmatsiia · 1974
- Stimulation of B-Lymphopoiesis by Administration of a Trimecaine-Based Ionic Compound in Cyclophosphamide-Induced Hematopoietic-Depressive Model.Molecules (Basel, Switzerland) · 2023
- Analytical Quality by Design-Compliant Development of a Cyclodextrin-Modified Micellar ElectroKinetic Chromatography Method for the Determination of Trimecaine and Its Impurities.Molecules (Basel, Switzerland) · 2023
via PubMed
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Encyclopedic overview
6 sectionsContents
- History
- Action mechanism, pharmacokinetics
- Indication
- Contraindication
- Adverse effects
- References
Trimecaine (systematic name (2,4,6-trimethylphenylcarbamoylmethyl)diethylammonium chloride, chemical formula C15H25ClN2O) is an organic compound used as a local anesthetic and cardial antiarrhythmic. It is white crystalline powder readily soluble in water and ethanol. It is an active ingredient in products available under trademarks Mesdicain, Mesocain, Mesokain and others.
==History== Trimecaine is probably a Czech discovery (in light of complex pharmacological and clinical evaluation and practical deployment) although its preparation was published by Löfgren in 1946.
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