TYMP

Also known as thymidine phosphorylase, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP

protein-coding gene in the species Homo sapiens

Gene data

TYMP

Name: thymidine phosphorylase
Type: protein-coding
Position: 50,525,752–50,530,326 (−)
Aliases: ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF
Ensembl: ENSG00000025708
RefSeq RNA: NM_001113755.3, NM_001113756.3, NM_001257988.1, NM_001257989.1, NM_001953.5
RefSeq protein: NP_001107227.1, NP_001107228.1, NP_001244917.1, NP_001244918.1, NP_001944.1

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012].