udenafil
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The drug udenafil is marketed under the trade name Zydena. It is within the PDE5 inhibitor class (which also includes avanafil, sildenafil, tadalafil, and vardenafil). Like other PDE5 inhibitors, it is used to treat erectile dysfunction. Udenafil was developed by Dong-A Pharmaceutical. It has fairly rapid onset of action (peak plasma concentration after 1 to 1.5 hours), and has long duration of action (plasma half-life of 11 to 13 hours). Udenafil's pharmacokinetics allows once-daily dosage (in addition to on-demand use). Typical doses are 100 and 200 mg. Udenafil is available in Korea, R
Research
227 papers- Udenafil for the treatment of erectile dysfunction.Therapeutics and clinical risk management · 2014
- Udenafil as a Therapeutic Option for Pulmonary Arterial Hypertension.Korean circulation journal · 2019
- The Fontan Udenafil Exercise Longitudinal Trial: Subgroup Analysis.Pediatric cardiology · 2023
- Design and rationale of the Fontan Udenafil Exercise Longitudinal (FUEL) trial.American heart journal · 2018
- Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells.Biomolecules & therapeutics · 2019
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 516.251875
- Has use
- medication
Show 3 more facts
- chemical formula
- C₂₅H₃₆N₆O₄S
- canonical SMILES
- CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)NCCC4CCCN4C)OCCC)C
- Commons category
- Udenafil
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
1 sectionsContents
- References
The drug udenafil is marketed under the trade name Zydena. It is within the PDE5 inhibitor class (which also includes avanafil, sildenafil, tadalafil, and vardenafil). Like other PDE5 inhibitors, it is used to treat erectile dysfunction. Udenafil was developed by Dong-A Pharmaceutical. It has fairly rapid onset of action (peak plasma concentration after 1 to 1.5 hours), and has long duration of action (plasma half-life of 11 to 13 hours). Udenafil's pharmacokinetics allows once-daily dosage (in addition to on-demand use). Typical doses are 100 and 200 mg. Udenafil is available in Korea, Russia, and the Philippines. It has not yet been approved for use in the United States by the U.S. Food and Drug Administration.
== References ==
Excerpted from Wikipedia’s “udenafil” article, available under the CC BY-SA 4.0 licence.
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