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GeneQ18033169· pop 6· linked from 6 articles

Also known as UNC5H3, unc-5 netrin receptor C

Netrin receptor UNC5C is a protein that in humans is encoded by the UNC5C gene.

Gene data

UNC5C
Name
unc-5 netrin receptor C
Type
protein-coding
Aliases
UNC5H3

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

unc-5 netrin receptor C

Symbol
UNC5C
Biotype
Protein coding
Organism
Homo sapiens
Location
4:95,162,504-95,549,206
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
2765
genomic end
96470357
genomic start
96083655
cytogenetic location
4q22.3
Sources (6)

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Contents
  • References
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Netrin receptor UNC5C is a protein that in humans is encoded by the UNC5C gene.

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.

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