Structure via PubChem · Public domain (PubChem)
WAY-208466
Sign in to saveAlso known as WAY-208,466
WAY-208466 is a potent and highly selective full agonist of the 5-HT6 receptor. It increases GABA levels in the cerebral cortex and tolerance does not appear to occur to this action upon chronic administration. Animal studies have shown that WAY-208466 produces antidepressant and anxiolytic effects in rodents and it may also be useful in the treatment of obsessive-compulsive disorder.
In the Vinony graph
Vinony's link graph records 1,586 inbound references to WAY-208466, and connects out to N-methylserotonin, glaucine and azasetron.
It is catalogued under topics including 3-Fluorophenyl compounds, 5-HT6 agonists and Chemical pages without DrugBank identifier.
Vinony links it to 4 Wikipedia language editions.
Chemical data
- Formula
- C17H18FN3O2S
- Molecular weight
- 347.4 g/mol
- IUPAC name
- 2-[3-(3-fluorophenyl)sulfonylpyrrolo[2,3-b]pyridin-1-yl]-N,N-dimethylethanamine
- SMILES
- CN(C)CCN1C=C(C2=C1N=CC=C2)S(=O)(=O)C3=CC=CC(=C3)F
- InChIKey
- SFSFIDVAEMDPIP-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 63.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 347.110376036
Show 3 more facts
- canonical SMILES
- CN(C)CCN1C=C(C2=C1N=CC=C2)S(=O)(=O)C3=CC=CC(=C3)F
- Commons category
- WAY-208,466
- chemical formula
- C₁₇H₁₈FN₃O₂S
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
{{Drugbox | image = WAY208466.png | image_class = skin-invert-image | alt = Skeletal formula of WAY-208,466 | width = 200 | IUPAC_name = 2-{3-[(3-Fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}-N,N-dimethylethanamine
| tradename = | pregnancy_category = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “WAY-208466” article, available under the CC BY-SA 4.0 licence.