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GeneQ18051905· pop 5· linked from 2 articles

Also known as PRG5, WAP1, dJ211D12.5, WAP four-disulfide core domain 5

WAP four-disulfide core domain protein 5 is a protein that in humans is encoded by the WFDC5 gene.

Gene data

WFDC5
Name
WAP four-disulfide core domain 5
Type
protein-coding
Aliases
PRG5, WAP1, dJ211D12.5

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

WAP four-disulfide core domain 5

Symbol
WFDC5
Biotype
Protein coding
Organism
Homo sapiens
Location
20:45,109,452-45,115,217
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
17072
genomic end
43743813
genomic start
43738093
cytogenetic location
20q13.12
Sources (4)

via Wikidata · CC0

~1 min read

Article

2 sections
Contents
  • References
  • Further reading

WAP four-disulfide core domain protein 5 is a protein that in humans is encoded by the WFDC5 gene.

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.

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